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小松 紀子
Noriko Komatsu, Ph.D.

東京大学大学院医学系研究科 免疫学 助教
E-mail address: koma-im[@]m.u-tokyo.ac.jp


原著論文、総説・著書(英文)

Komatsu N, Takayanagi H. Immune-bone interplay in the structural damage in rheumatoid arthritis.Clin Exp Immunol. doi: 10.1111/cei.13188. (2018) [PubMed]

Tsukasaki M, Komatsu N, Nagashima K, Nitta T, Pluemsakunthai W, Shukunami C, Iwakura Y, Nakashima T, Okamoto K, Takayanagi H.
Host defense against oral microbiota by bone-damaging T cells. Nat Commun.9:701(2018) [PubMed]

Tsukasaki M, Hamada K, Okamoto K Nagashima K, Terashima A, Komatsu N, Win S, Okamura T, Nitta T, Yasuda H, Penninger JM, Takayanagi H.
LOX Fails to Substitute for RANKL in Osteoclastogenesis. J Bone Miner Res. 32(3):434-439. (2017) [PubMed]

Guerrini MM, Okamoto K, Komatsu N, Sawa S, Danks L, Penninger JM, Nakashima T, Takayanagi H.
Inhibition of the TNF Family Cytokine RANKL Prevents Autoimmune Inflammation in the Central Nervous System. Immunity. 43(6):1174-85 (2015) [PubMed]

Komatsu N, Takayanagi H.
Regulatory T cells in Arthritis.Prog Mol Biol Transl Sci.136:207-15 (2015) [PubMed]

Takaba H, Morishita Y, Tomofuji Y, Danks L, Nitta T, Komatsu N, Kodama T, Takayanagi H.
Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance.Cell.163(4):975-87 (2015) [PubMed]

Danks L, Komatsu N, Guerrini MM, Sawa S, Armaka M, Kollias G, Nakashima T, Takayanagi H.
RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation.Ann Rheum Dis.75(6):1187-95. (2016) [PubMed]

Negishi-Koga T, Gober HJ, Sumiya E, Komatsu N, Okamoto K, Sawa S, Suematsu A, Suda T, Sato K, Takai T, Takayanagi H.
Immune complexes regulate bone metabolism through FcRγ signalling.Nat Commun.6:6637. (2015) [PubMed]

Komatsu N, Takayanagi H. Arthritogenic T cells in autoimmune arthritis. Int J Biochem Cell Biol. 58:92-6 (2015) [PubMed]

Komatsu, N., Okamoto, K., Sawa, S., Nakashima, T., Oh-Hora, M., Kodama, T., Tanaka, S., Bluestone, J.A., Takayanagi, H.
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nature Medicine. 20(1), 62-8 (2014) [Pubmed]

Oh-Hora, M., Komatsu, N., Pishyareh, M., Feske, S., Hori, S., Taniguchi, M., Rao, A., Takayanagi, H.
Agonist-Selected T Cell Development Requires Strong T Cell Receptor Signaling and Store-Operated Calcium Entry. Immunity. 38(5), 881-895 (2013) [Pubmed]

Komatsu, N., Takayanagi, H.
Autoimmune arthritis: the interface between the immune system and joints. Adv Immunol. 115, 45-71 (2012) [Pubmed]

Komatsu, N., Takayanagi, H.
Inflammation and bone destruction in arthritis: synergistic activity of immune and mesenchymal cells in joints. Front Immunol. 3, 77 (2012) [Pubmed]

Negishi-Koga, T., Shinohara, M., Komatsu, N., Bito, H., Kodama, T., Friedel, R.H., Takayanagi, H.
Suppression of bone formation by osteoclastic expression of semaphorin 4D. Nature Medicine. 17(11), 1473-80, (2011) [Pubmed]

Tsuji, M.*, Komatsu, N.*, Kawamoto, S.*, Suzuki, K., Kanagawa, O., Honjo, T., Hori, S., Fagarasan, S.
Preferential generation of follicular B helper T (TFH) cells from Foxp3+T cells in gut Peyer’s patches. Science. 323(5920), 1488-92. (2009) *equally contributed [Pubmed]

Komatsu, N., Mariotti-Ferrandiz, M.E., Wang, Y., Malissen, B., Waldmann, H., Hori, S.
Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci U S A. 106(6), 1903-8 (2009) [Pubmed]

Komatsu, N., Waki, M., Sue, M., Tokuda, C., Kasaoka, T., Nakajima, M., Higashi, N., Irimura, T.
Heparanase expression in B16 melanoma cells and peripheral blood neutrophils before and after extravasation detected by novel anti-mouse heparanase monoclonal antibodies. J Immunol Methods. 331(1-2), 82-93 (2008) [Pubmed]

Komatsu, N., Hori, S.
Full restoration of peripheral Foxp3+ regulatory T cell pool by radioresistant host cells in scurfy bone marrow chimeras. Proc Natl Acad Sci U S A. 104(21), 8959-64 (2007) [Pubmed]

Sato, K., Komatsu, N., Higashi, N., Imai, Y., Irimura, T.
Granulation tissue formation by nonspecific inflammatory agent occurs independently of macrophage galactose-type C-type lectin-1. Clin Immunol. 115(1), 47-50 (2005) [Pubmed]